Glutathione During Pregnancy and Breastfeeding: Is It Safe?

On this page 6 sections
  1. Why isn’t glutathione recommended in pregnancy?
  2. Tablets, creams, drips: form by form
  3. Pregnancy pigmentation is common, and often temporary
  4. Gentler ways to look after your skin right now
  5. After breastfeeding
  6. Common questions

Quick answer

Is glutathione safe during pregnancy? There simply isn’t enough research to call it safe. While you’re pregnant or breastfeeding, avoid glutathione tablets, injections and IV drips, and ask your doctor before using any glutathione cream. Pregnancy pigmentation often fades after delivery, and gentle care with sunscreen is the safest approach until then.

Lots of women find their skin darkens during pregnancy. It might be patches on the face, a darker neck or underarms, or a line down the belly, and it’s natural to wonder if glutathione could help. Your baby’s safety comes first, so here’s what we know, and what we don’t.

Your body makes its own glutathione, and it does important work during pregnancy. The problem is with taking extra. There are no good studies on glutathione tablets, injections or high-strength skincare in pregnant or breastfeeding women, and without that research, doctors can’t tell you it’s safe.

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Tablets, creams, drips: form by form

Form During pregnancy / breastfeeding
Tablets, capsules, effervescent Avoid, unless your doctor prescribes it for a medical reason
Injections and IV drips Avoid
Creams and serums Ask your doctor first, because many brightening creams contain other actives too
Glutathione-rich foods Fine as part of a normal, balanced diet

Pregnancy pigmentation is common, and often temporary

Pregnancy hormones push up melanin, the pigment that colours your skin. You might notice:

  • Melasma, sometimes called the “mask of pregnancy”, which shows up as brown patches on the cheeks, forehead or upper lip
  • A darker neck, underarms or inner thighs
  • Linea nigra, a dark line running down the belly

Many of these changes fade by themselves in the months after your baby arrives. You can read more about melasma here.

Gentler ways to look after your skin right now

  • Wear sunscreen every day. Many doctors prefer mineral sunscreens (zinc oxide or titanium dioxide) during pregnancy.
  • Stay in the shade and wear a hat when you’re outdoors.
  • Use a gentle cleanser and moisturiser, and leave out harsh scrubs and any new strong actives for now.
  • Ask your doctor or dermatologist which brightening ingredients, if any, are right for you.
  • Eat well. Vegetables, protein, fruit and nuts support your body’s own antioxidants (see foods that boost glutathione).

After breastfeeding

Once you’ve stopped breastfeeding, and your doctor is happy with it, you can think about a glutathione cream if the pigmentation is still there. Do a patch test first, start slowly, and give it 8 to 12 weeks.

Common questions

I used glutathione before I knew I was pregnant. Should I worry?
Stop using it and let your doctor know. They can advise you based on what you used and how much. Try not to panic.

Can I use glutathione while trying to conceive?
It makes sense to stop supplements once you’re planning a pregnancy, and to talk through your skincare with your doctor.

Is glutathione soap safe in pregnancy?
Soap is rinsed off quickly, but it may have other ingredients in it. Check with your doctor, and stick to gentle, fragrance-free products.

For more on safety, read glutathione side effects and who should avoid it.


This article is for general information only and is not medical advice. Always talk to your obstetrician or doctor before using any supplement or skincare product while pregnant or breastfeeding.

Written bySam S

Founder of Beauty Mart, Bhatkal, and Glutanex India. Sam started The Glutathione to give Indian readers honest, research-based answers about glutathione. How we write and check our articles

This article is for general information, not medical advice. Talk to a doctor or dermatologist before starting any supplement or treatment. Disclaimer · Disclosure